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High glucose induces apoptosis via upregulation of Bim expression in proximal tubule epithelial cells

Diabetic nephropathy is the primary cause of end-stage renal disease. Apoptosis of tubule epithelial cells is a major feature of diabetic nephropathy. The mechanisms of high glucose (HG) induced apoptosis are not fully understood. Here we demonstrated that, HG induced apoptosis via upregulating the...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Qian, Dong, Jian-Jun, Cai, Tian, Shen, Xue, Zhou, Xiao-Jun, Liao, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421832/
https://www.ncbi.nlm.nih.gov/pubmed/28445931
http://dx.doi.org/10.18632/oncotarget.15491