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Pirfenidone normalizes the tumor microenvironment to improve chemotherapy

Normalization of the tumor microenvironment by selectively targeting components of the tumor extracellular matrix has been recently proposed to have the potential to decompress tumor blood vessels, increase vessel perfusion and thus, improve drug delivery and the efficacy of cancer therapy. Therefor...

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Detalles Bibliográficos
Autores principales: Polydorou, Christiana, Mpekris, Fotios, Papageorgis, Panagiotis, Voutouri, Chrysovalantis, Stylianopoulos, Triantafyllos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421866/
https://www.ncbi.nlm.nih.gov/pubmed/28445938
http://dx.doi.org/10.18632/oncotarget.15534