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Pirfenidone normalizes the tumor microenvironment to improve chemotherapy
Normalization of the tumor microenvironment by selectively targeting components of the tumor extracellular matrix has been recently proposed to have the potential to decompress tumor blood vessels, increase vessel perfusion and thus, improve drug delivery and the efficacy of cancer therapy. Therefor...
Autores principales: | Polydorou, Christiana, Mpekris, Fotios, Papageorgis, Panagiotis, Voutouri, Chrysovalantis, Stylianopoulos, Triantafyllos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421866/ https://www.ncbi.nlm.nih.gov/pubmed/28445938 http://dx.doi.org/10.18632/oncotarget.15534 |
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