Cargando…
EWS-FLI1 confers exquisite sensitivity to NAMPT inhibition in Ewing sarcoma cells
Ewing sarcoma (EwS) is the second most common bone cancer in children and adolescents with a high metastatic potential. EwS development is driven by a specific chromosomal translocation resulting in the generation of a chimeric EWS-ETS transcription factor, most frequently EWS-FLI1. Nicotinamide ade...
Autores principales: | , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421879/ https://www.ncbi.nlm.nih.gov/pubmed/28160567 http://dx.doi.org/10.18632/oncotarget.14976 |