Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer

Many human cancers have been reported to have enhanced expression of the immune checkpoint molecule programmed death-ligand 1 (PD-L1), which binds to programmed cell death-1 (PD-1) expressed on immune cells. PD-L1/PD-1 plays a role in inhibition of antitumor immunity by inducing T cell apoptosis and...

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Detalles Bibliográficos
Autores principales: Tanaka, Tsutomu, Kutomi, Goro, Kajiwara, Toshimitsu, Kukita, Kazuharu, Kochin, Vitaly, Kanaseki, Takayuki, Tsukahara, Tomohide, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Okamoto, Yoshiharu, Hirata, Koichi, Sato, Noriyuki, Tamura, Yasuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421881/
https://www.ncbi.nlm.nih.gov/pubmed/28160557
http://dx.doi.org/10.18632/oncotarget.14960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421881/
https://www.ncbi.nlm.nih.gov/pubmed/28160557
http://dx.doi.org/10.18632/oncotarget.14960

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