Cargando…

Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer

Many human cancers have been reported to have enhanced expression of the immune checkpoint molecule programmed death-ligand 1 (PD-L1), which binds to programmed cell death-1 (PD-1) expressed on immune cells. PD-L1/PD-1 plays a role in inhibition of antitumor immunity by inducing T cell apoptosis and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanaka, Tsutomu, Kutomi, Goro, Kajiwara, Toshimitsu, Kukita, Kazuharu, Kochin, Vitaly, Kanaseki, Takayuki, Tsukahara, Tomohide, Hirohashi, Yoshihiko, Torigoe, Toshihiko, Okamoto, Yoshiharu, Hirata, Koichi, Sato, Noriyuki, Tamura, Yasuaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421881/ https://www.ncbi.nlm.nih.gov/pubmed/28160557 http://dx.doi.org/10.18632/oncotarget.14960

Ejemplares similares

Cancer-associated oxidoreductase ERO1-α drives the production of VEGF via oxidative protein folding and regulating the mRNA level
por: Tanaka, Tsutomu, et al.
Publicado: (2016)

Heat shock protein 90 targets a chaperoned peptide to the static early endosome for efficient cross-presentation by human dendritic cells
por: Tanaka, Tsutomu, et al.
Publicado: (2015)

Immune responses to human cancer stem‐like cells/cancer‐initiating cells
por: Hirohashi, Yoshihiko, et al.
Publicado: (2015)

Ectopically Expressed Variant Form of Sperm Mitochondria-Associated Cysteine-Rich Protein Augments Tumorigenicity of the Stem Cell Population of Lung Adenocarcinoma Cells
por: Takahashi, Akari, et al.
Publicado: (2013)

Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells
por: Morita, Rena, et al.
Publicado: (2014)

Cytotoxic T lymphocytes: Sniping cancer stem cells
por: Hirohashi, Yoshihiko, et al.
Publicado: (2012)

ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway
por: Ogawa, Tadashi, et al.
Publicado: (2017)

Fundamental and Essential Knowledge for Pathologists Engaged in the Research and Practice of Immune Checkpoint Inhibitor-Based Cancer Immunotherapy
por: Kubo, Terufumi, et al.
Publicado: (2021)

Case report: Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine
por: Shima, Hiroaki, et al.
Publicado: (2018)

Development of an artificial antibody specific for HLA/peptide complex derived from cancer stem-like cell/cancer-initiating cell antigen DNAJB8
por: Tadano, Hiroki, et al.
Publicado: (2020)

Implication of chemo‐resistant memory T cells for immune surveillance in patients with sarcoma receiving chemotherapy
por: Shibayama, Yuji, et al.
Publicado: (2017)

Development of a T‐cell receptor multimer with high avidity for detecting a naturally presented tumor‐associated antigen on osteosarcoma cells
por: Watanabe, Kazue, et al.
Publicado: (2018)

IL‐13 modulates ∆Np63 levels causing altered expression of barrier‐ and inflammation‐related molecules in human keratinocytes: A possible explanation for chronicity of atopic dermatitis
por: Kubo, Terufumi, et al.
Publicado: (2021)

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480
por: Takaya, Akari, et al.
Publicado: (2016)

Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress
por: Saijo, Hiroshi, et al.
Publicado: (2016)

Spatiotemporal metabolic dynamics of the photosensitizer talaporfin sodium in carcinoma and sarcoma
por: Saito, Takuma, et al.
Publicado: (2020)

Cisplatin‐induced HSF1‐HSP90 axis enhances the expression of functional PD‐L1 in oral squamous cell carcinoma
por: Sasaya, Takashi, et al.
Publicado: (2022)

Identification of a novel human memory T-cell population with the characteristics of stem-like chemo-resistance
por: Murata, Kenji, et al.
Publicado: (2016)

Osteosarcoma‐initiating cells show high aerobic glycolysis and attenuation of oxidative phosphorylation mediated by LIN28B
por: Mizushima, Emi, et al.
Publicado: (2019)

Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA‐A24‐positive pancreatic adenocarcinoma
por: Shima, Hiroaki, et al.
Publicado: (2019)

ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD
por: Kawai, Noriko, et al.
Publicado: (2019)

Ovarian Cancer Stem Cells Are Enriched in Side Population and Aldehyde Dehydrogenase Bright Overlapping Population
por: Yasuda, Kazuyo, et al.
Publicado: (2013)

Cellular stress induces cancer stem‐like cells through expression of DNAJB8 by activation of heat shock factor 1
por: Kusumoto, Hiroki, et al.
Publicado: (2018)

GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis
por: Inoue, Ryuta, et al.
Publicado: (2017)

Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP27
por: Yasuda, Kazuyo, et al.
Publicado: (2017)

Non‐bacterial cystitis with increased expression of programmed death‐ligand 1 in the urothelium: An unusual immune‐related adverse event during treatment with pembrolizumab for lung adenocarcinoma
por: Ueki, Yohei, et al.
Publicado: (2020)

Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series
por: Kubo, Terufumi, et al.
Publicado: (2019)

YTHDC2 Promotes Malignant Phenotypes of Breast Cancer Cells
por: Tanabe, Atsushi, et al.
Publicado: (2022)

Non-neoplastic Fallopian Tube Epithelium Carrying Gene Mutations of a Novel SOX2 Repressor Region is Soil of High-grade Serous Ovarian Cancer
por: Hirohashi, Yoshihiko, et al.
Publicado: (2016)

Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy
por: Horibe, Ryota, et al.
Publicado: (2017)

Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer
por: Honma, Ichiya, et al.
Publicado: (2009)

A quest for therapeutic antigens in bone and soft tissue sarcoma
por: Kawaguchi, Satoshi, et al.
Publicado: (2005)

The Role of ERO1α in Modulating Cancer Progression and Immune Escape
por: Johnson, Brennan D., et al.
Publicado: (2020)

Exploring olfactory receptor family 7 subfamily C member 1 as a novel oral cancer stem cell target for immunotherapy
por: Miyamoto, Sho, et al.
Publicado: (2023)

Ero1-α and PDIs constitute a hierarchical electron transfer network of endoplasmic reticulum oxidoreductases
por: Araki, Kazutaka, et al.
Publicado: (2013)

Identification of characteristic subepithelial surface granulomatosis in immune‐related adverse event‐associated enterocolitis
por: Kubo, Terufumi, et al.
Publicado: (2021)

Dnajb8, a Member of the Heat Shock Protein 40 Family Has a Role in the Tumor Initiation and Resistance to Docetaxel but Is Dispensable for Stress Response
por: Yamashita, Masamichi, et al.
Publicado: (2016)

High Expression of CD109 Antigen Regulates the Phenotype of Cancer Stem-Like Cells/Cancer-Initiating Cells in the Novel Epithelioid Sarcoma Cell Line ESX and Is Related to Poor Prognosis of Soft Tissue Sarcoma
por: Emori, Makoto, et al.
Publicado: (2013)

Identification of novel human leukocyte antigen‐A*11:01‐restricted cytotoxic T‐lymphocyte epitopes derived from osteosarcoma antigen papillomavirus binding factor
por: Li, Dongliang, et al.
Publicado: (2019)

Proteogenomic identification of an immunogenic HLA class I neoantigen in mismatch repair–deficient colorectal cancer tissue
por: Hirama, Tomomi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_s0uq9o319thrqdu0nias91s7ev