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NF-κB1, c-Rel, and ELK1 inhibit miR-134 expression leading to TAB1 upregulation in paclitaxel-resistant human ovarian cancer

The mechanism by which the transcription factors inhibit the miRNA expression in ovarian cancer chemoresistance is unclear. The present study investigated the mechanism underlying the transcriptional repression of miR-134 in chemoresistant serous epithelial ovarian cancer. The results demonstrate th...

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Detalles Bibliográficos
Autores principales: Shuang, Ting, Wang, Min, Zhou, Yingying, Shi, Cong, Wang, Dandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421894/
https://www.ncbi.nlm.nih.gov/pubmed/28206956
http://dx.doi.org/10.18632/oncotarget.15267