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An autocrine/paracrine circuit of growth differentiation factor (GDF) 15 has a role for maintenance of breast cancer stem-like cells

Cancer stem cells are thought to be responsible for tumor growth, recurrence, and resistance to conventional cancer therapy. However, it is still unclear how they are maintained in tumor tissues. Here, we show that the growth differentiation factor 15 (GDF15), a member of the TGFβ family, may mainta...

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Detalles Bibliográficos
Autores principales: Sasahara, Asako, Tominaga, Kana, Nishimura, Tatsunori, Yano, Masao, Kiyokawa, Etsuko, Noguchi, Miki, Noguchi, Masakuni, Kanauchi, Hajime, Ogawa, Toshihisa, Minato, Hiroshi, Tada, Keiichiro, Seto, Yasuyuki, Tojo, Arinobu, Gotoh, Noriko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421895/
https://www.ncbi.nlm.nih.gov/pubmed/28206960
http://dx.doi.org/10.18632/oncotarget.15276