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Targeting the stress oncoprotein LEDGF/p75 to sensitize chemoresistant prostate cancer cells to taxanes

Prostate cancer (PCa) is associated with chronic prostate inflammation resulting in activation of stress and pro-survival pathways that contribute to disease progression and chemoresistance. The stress oncoprotein lens epithelium-derived growth factor p75 (LEDGF/p75), also known as DFS70 autoantigen...

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Detalles Bibliográficos
Autores principales: Ríos-Colón, Leslimar, Cajigas-Du Ross, Christina K., Basu, Anamika, Elix, Catherine, Alicea-Polanco, Ivana, Sanchez, Tino W., Radhakrishnan, Vinodh, Chen, Chien-Shing, Casiano, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421899/
https://www.ncbi.nlm.nih.gov/pubmed/28212536
http://dx.doi.org/10.18632/oncotarget.15323