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The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung

Mast cell secretory granules are densely packed with various bioactive mediators including proteases of chymase, tryptase and CPA3 type. Previous studies have indicated that mast cells can affect the outcome of melanoma but the contribution of the mast cell granule proteases to such effects has not...

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Detalles Bibliográficos
Autores principales: Grujic, Mirjana, Paivandy, Aida, Gustafson, Ann-Marie, Thomsen, Allan R., Öhrvik, Helena, Pejler, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421910/
https://www.ncbi.nlm.nih.gov/pubmed/28212574
http://dx.doi.org/10.18632/oncotarget.15339