Methylation-mediated silencing of microRNA-211 promotes cell growth and epithelial to mesenchymal transition through activation of the AKT/β-catenin pathway in GBM

Aberrant expression of miR-211 has frequently been reported in cancer studies; however, its role in glioblastoma multiforme (GBM) has not been examined in detail. We investigated the function and the underlying mechanism of miR-211 in GBM. We revealed that miR-211 was downregulated in GBM tissues an...

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Detalles Bibliográficos
Autores principales: Li, Weidong, Miao, Xiaobo, Liu, Lingling, Zhang, Yue, Jin, Xuejun, Luo, Xiaojun, Gao, Hai, Deng, Xubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421919/
https://www.ncbi.nlm.nih.gov/pubmed/28445937
http://dx.doi.org/10.18632/oncotarget.15531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421919/
https://www.ncbi.nlm.nih.gov/pubmed/28445937
http://dx.doi.org/10.18632/oncotarget.15531

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