MiR-148a increases glioma cell migration and invasion by downregulating GADD45A in human gliomas with IDH1 R132H mutations

High-grade gliomas are severe tumors with poor prognosis. An R132H mutation in the isocitrate dehydrogenase (IDH1) gene prolongs the life of glioma patients. In this study, we investigated which genes are differentially regulated in IDH1 wild type (IDH1(WT)) or IDH1 R132H mutation (IDH1(R132H)) glio...

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Detalles Bibliográficos
Autores principales: Cui, Daming, Sajan, Pandey, Shi, Jinlong, Shen, Yiwen, Wang, Ke, Deng, Xianyu, Zhou, Lin, Hu, Pingping, Gao, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421935/
https://www.ncbi.nlm.nih.gov/pubmed/28445981
http://dx.doi.org/10.18632/oncotarget.15867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421935/
https://www.ncbi.nlm.nih.gov/pubmed/28445981
http://dx.doi.org/10.18632/oncotarget.15867

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