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Integrated analysis of promoter methylation and expression of telomere related genes in breast cancer

Telomeres at the ends of eukaryotic chromosomes play a critical role in tumorgenesis. Using microfluidic PCR and next-generation bisulfite sequencing technology, we investigated the promoter methylation of 29 telomere related genes in paired tumor and normal tissues from 184 breast cancer patients....

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Detalles Bibliográficos
Autores principales: Heng, Jianfu, Zhang, Fan, Guo, Xinwu, Tang, Lili, Peng, Limin, Luo, Xipeng, Xu, Xunxun, Wang, Shouman, Dai, Lizhong, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421942/
https://www.ncbi.nlm.nih.gov/pubmed/28424414
http://dx.doi.org/10.18632/oncotarget.16036