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The soy-derived peptide Lunasin inhibits invasive potential of melanoma initiating cells

Lunasin is a 44 amino acid peptide with multiple functional domains including an aspartic acid tail, an RGD domain, and a chromatin-binding helical domain. We recently showed that Lunasin induced a phenotype switch of cancer initiating cells (CIC) out of the stem compartment by inducing melanocyte-a...

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Detalles Bibliográficos
Autores principales: Shidal, Chris, Inaba, Jun-Ichi, Yaddanapudi, Kavitha, Davis, Keith R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421948/
https://www.ncbi.nlm.nih.gov/pubmed/28424421
http://dx.doi.org/10.18632/oncotarget.16066