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Limited impact of intratumour heterogeneity on molecular risk assignment in endometrial cancer

INTRODUCTION: Individual prediction of tumour behaviour based on molecular markers may refine adjuvant treatment strategies in endometrial cancer (EC). As these molecular alterations are determined in a small tumour fraction, high intratumour heterogeneity may interfere with correct risk prediction....

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Detalles Bibliográficos
Autores principales: van Esterik, Manouk, Van Gool, Inge C., de Kroon, Cor D., Nout, Remi A., Creutzberg, Carien L., Smit, Vincent T.H.B.M., Bosse, Tjalling, Stelloo, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421949/
https://www.ncbi.nlm.nih.gov/pubmed/28424422
http://dx.doi.org/10.18632/oncotarget.16067