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Trabectedin and Campthotecin Synergistically Eliminate Cancer Stem Cells in Cell-of-Origin Sarcoma Models()

Trabectedin has been approved for second-line treatment of soft tissue sarcomas. However, its efficacy to target sarcoma initiating cells has not been addressed yet. Here, we used pioneer models of myxoid/round cell liposarcoma (MRCLS) and undifferentiated pleomorphic sarcoma (UPS) developed from tr...

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Detalles Bibliográficos
Autores principales: Martinez-Cruzado, Lucia, Tornin, Juan, Rodriguez, Aida, Santos, Laura, Allonca, Eva, Fernandez-Garcia, Maria Teresa, Astudillo, Aurora, Garcia-Pedrero, Juana Maria, Rodriguez, Rene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421973/
https://www.ncbi.nlm.nih.gov/pubmed/28494349
http://dx.doi.org/10.1016/j.neo.2017.03.004