Cargando…
Trabectedin and Campthotecin Synergistically Eliminate Cancer Stem Cells in Cell-of-Origin Sarcoma Models()
Trabectedin has been approved for second-line treatment of soft tissue sarcomas. However, its efficacy to target sarcoma initiating cells has not been addressed yet. Here, we used pioneer models of myxoid/round cell liposarcoma (MRCLS) and undifferentiated pleomorphic sarcoma (UPS) developed from tr...
Autores principales: | Martinez-Cruzado, Lucia, Tornin, Juan, Rodriguez, Aida, Santos, Laura, Allonca, Eva, Fernandez-Garcia, Maria Teresa, Astudillo, Aurora, Garcia-Pedrero, Juana Maria, Rodriguez, Rene |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5421973/ https://www.ncbi.nlm.nih.gov/pubmed/28494349 http://dx.doi.org/10.1016/j.neo.2017.03.004 |
Ejemplares similares
-
Inhibition of SP1 by the mithramycin analog EC-8042 efficiently targets tumor initiating cells in sarcoma
por: Tornin, Juan, et al.
Publicado: (2016) -
Aldh1 Expression and Activity Increase During Tumor Evolution in Sarcoma Cancer Stem Cell Populations
por: Martinez-Cruzado, Lucia, et al.
Publicado: (2016) -
SOX2 Expression and Transcriptional Activity Identifies a Subpopulation of Cancer Stem Cells in Sarcoma with Prognostic Implications
por: Menendez, Sofia T., et al.
Publicado: (2020) -
New Chondrosarcoma Cell Lines with Preserved Stem Cell Properties to Study the Genomic Drift During In Vitro/In Vivo Growth
por: Rey, Veronica, et al.
Publicado: (2019) -
Trabectedin in Soft Tissue Sarcomas
por: Petek, Bradley J., et al.
Publicado: (2015)