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Dual interaction of scaffold protein Tim44 of mitochondrial import motor with channel-forming translocase subunit Tim23

Proteins destined for the mitochondrial matrix are targeted to the inner membrane Tim17/23 translocon by their presequences. Inward movement is driven by the matrix-localized, Hsp70-based motor. The scaffold Tim44, interacting with the matrix face of the translocon, recruits other motor subunits and...

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Detalles Bibliográficos
Autores principales: Ting, See-Yeun, Yan, Nicholas L, Schilke, Brenda A, Craig, Elizabeth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422074/
https://www.ncbi.nlm.nih.gov/pubmed/28440746
http://dx.doi.org/10.7554/eLife.23609