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Dual interaction of scaffold protein Tim44 of mitochondrial import motor with channel-forming translocase subunit Tim23
Proteins destined for the mitochondrial matrix are targeted to the inner membrane Tim17/23 translocon by their presequences. Inward movement is driven by the matrix-localized, Hsp70-based motor. The scaffold Tim44, interacting with the matrix face of the translocon, recruits other motor subunits and...
Autores principales: | Ting, See-Yeun, Yan, Nicholas L, Schilke, Brenda A, Craig, Elizabeth A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422074/ https://www.ncbi.nlm.nih.gov/pubmed/28440746 http://dx.doi.org/10.7554/eLife.23609 |
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