Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation

Relaxases play essential roles in conjugation, the main process by which bacteria exchange genetic material, notably antibiotic resistance genes. They are bifunctional enzymes containing a trans-esterase activity, which is responsible for nicking the DNA strand to be transferred and for covalent att...

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Detalles Bibliográficos
Autores principales: Ilangovan, Aravindan, Kay, Christopher W.M., Roier, Sandro, El Mkami, Hassane, Salvadori, Enrico, Zechner, Ellen L., Zanetti, Giulia, Waksman, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422253/
https://www.ncbi.nlm.nih.gov/pubmed/28457609
http://dx.doi.org/10.1016/j.cell.2017.04.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422253/
https://www.ncbi.nlm.nih.gov/pubmed/28457609
http://dx.doi.org/10.1016/j.cell.2017.04.010

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