Low‐dose interleukin‐2 promotes STAT‐5 phosphorylation, T(reg) survival and CTLA‐4‐dependent function in autoimmune liver diseases

CD4(+)CD25(high)CD127(low)forkhead box protein 3 (FoxP3(+)) regulatory T cells (T(reg)) are essential for the maintenance of peripheral tolerance. Impaired T(reg) function and an imbalance between effector and T(regs) contribute to the pathogenesis of autoimmune diseases. We reported recently that t...

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Detalles Bibliográficos
Autores principales: Jeffery, H. C., Jeffery, L. E., Lutz, P., Corrigan, M., Webb, G. J., Hirschfield, G. M., Adams, D. H., Oo, Y. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422719/
https://www.ncbi.nlm.nih.gov/pubmed/28176332
http://dx.doi.org/10.1111/cei.12940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422719/
https://www.ncbi.nlm.nih.gov/pubmed/28176332
http://dx.doi.org/10.1111/cei.12940

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