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Targeted siRNA delivery reduces nitric oxide mediated cell death after spinal cord injury

BACKGROUND: Traumatic spinal cord injury (SCI) includes the primary insult as well as a sequela of biochemical and cellular cascades that amplifies the initial injury. This degenerative process, known as secondary injury, is often mediated by both reactive oxygen and nitrogen species released from d...

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Detalles Bibliográficos
Autores principales: Gao, Wen, Li, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422875/
https://www.ncbi.nlm.nih.gov/pubmed/28482882
http://dx.doi.org/10.1186/s12951-017-0272-7