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Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese mice

BACKGROUND: Saturated fatty acids have been shown to cause insulin resistance and low-grade chronic inflammation, whereas unsaturated fatty acids suppress inflammation via G-protein coupled receptor 120 (GPR120) in macrophages. However, the anti-inflammatory effects of unsaturated fatty acids in adi...

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Detalles Bibliográficos
Autores principales: Yamada, Hodaka, Umemoto, Tomio, Kakei, Masafumi, Momomura, Shin-ichi, Kawakami, Masanobu, Ishikawa, San-e, Hara, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422876/
https://www.ncbi.nlm.nih.gov/pubmed/28503189
http://dx.doi.org/10.1186/s12986-017-0188-0