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The drive to generate multiple forms of oncogenic cyclin D1 transcripts in mantle cell lymphoma

Alternative polyadenylation is a rapidly emerging form of gene regulation, which in its simplest form, enables the generation of mRNA transcripts that code for the same protein but have 3′UTRs of different lengths and regulatory content. For oncogenes, shorter 3′UTRs would be preferred as a mechanis...

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Detalles Bibliográficos
Autor principal: Masamha, Chioniso Patience
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422887/
https://www.ncbi.nlm.nih.gov/pubmed/28503306
http://dx.doi.org/10.1186/s40364-017-0094-7