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Sclerostin activity plays a key role in the negative effect of glucocorticoid signaling on osteoblast function in mice

Stress during prenatal development is correlated with detrimental cognitive and behavioral outcomes in offspring. However, the long-term impact of prenatal stress (PS) and disrupted glucocorticoid signaling on bone mass and strength is not understood. In contrast, the detrimental effect of lead (Pb)...

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Detalles Bibliográficos
Autores principales: Beier, Eric E, Sheu, Tzong-Jen, Resseguie, Emily A, Takahata, Masahiko, Awad, Hani A, Cory-Slechta, Deborah A, Puzas, J Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422922/
https://www.ncbi.nlm.nih.gov/pubmed/28529816
http://dx.doi.org/10.1038/boneres.2017.13