Mucin 1, a signal transduction membrane-bound mucin, is present in human disc tissue and is downregulated in vitro by exposure to IL-1ß or TNF-α

BACKGROUND: Back pain and disc degeneration have a growing socioeconomic healthcare impact. Mucin 1 (MUC1) is a transmembrane glycoprotein whose extracellular and intracellular domains participate in cellular signaling. Little is currently known about the presence or role of MUC1 in human disc degen...

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Detalles Bibliográficos
Autores principales: Gruber, Helen E., Ingram, Jane A., Hoelscher, Gretchen L., Marrero, Emilio, Hanley, Edward N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422927/
https://www.ncbi.nlm.nih.gov/pubmed/28482827
http://dx.doi.org/10.1186/s12891-017-1541-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422927/
https://www.ncbi.nlm.nih.gov/pubmed/28482827
http://dx.doi.org/10.1186/s12891-017-1541-1

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