Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells

BACKGROUND: Epigenome editing is expected to manipulate transcription and cell fates and to elucidate the gene expression mechanisms in various cell types. For functional epigenome editing, assessing the chromatin context-dependent activity of artificial epigenetic modifier is required. RESULTS: In...

Descripción completa

Detalles Bibliográficos
Autores principales: Okada, Masahiro, Kanamori, Mitsuhiro, Someya, Kazue, Nakatsukasa, Hiroko, Yoshimura, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422987/
https://www.ncbi.nlm.nih.gov/pubmed/28503202
http://dx.doi.org/10.1186/s13072-017-0129-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422987/
https://www.ncbi.nlm.nih.gov/pubmed/28503202
http://dx.doi.org/10.1186/s13072-017-0129-1

Ejemplares similares