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Stabilization of Foxp3 expression by CRISPR-dCas9-based epigenome editing in mouse primary T cells
BACKGROUND: Epigenome editing is expected to manipulate transcription and cell fates and to elucidate the gene expression mechanisms in various cell types. For functional epigenome editing, assessing the chromatin context-dependent activity of artificial epigenetic modifier is required. RESULTS: In...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5422987/ https://www.ncbi.nlm.nih.gov/pubmed/28503202 http://dx.doi.org/10.1186/s13072-017-0129-1 |