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Towards a new standardized method for circulating miRNAs profiling in clinical studies: Interest of the exogenous normalization to improve miRNA signature accuracy

Circulating miRNAs are promising biomarkers in oncology but have not yet been implemented in the clinic given the lack of concordance across studies. In order to increase the cross‐studies reliability, we attempted to reduce and to control the circulating miRNA expression variability between patient...

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Detalles Bibliográficos
Autores principales: Vigneron, Nicolas, Meryet-Figuière, Matthieu, Guttin, Audrey, Issartel, Jean-Paul, Lambert, Bernard, Briand, Mélanie, Louis, Marie-Hélène, Vernon, Mégane, Lebailly, Pierre, Lecluse, Yannick, Joly, Florence, Krieger, Sophie, Lheureux, Stéphanie, Clarisse, Bénédicte, Leconte, Alexandra, Gauduchon, Pascal, Poulain, Laurent, Denoyelle, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423189/
https://www.ncbi.nlm.nih.gov/pubmed/27083764
http://dx.doi.org/10.1016/j.molonc.2016.03.005