Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38α activation

Polycomb proteins are critical chromatin modifiers that regulate stem cell differentiation via transcriptional repression. In skeletal muscle progenitors Enhancer of zeste homologue 2 (EZH2), the catalytic subunit of Polycomb Repressive Complex 2 (PRC2), contributes to maintain the chromatin of musc...

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Detalles Bibliográficos
Autores principales: Consalvi, Silvia, Brancaccio, Arianna, Dall'Agnese, Alessandra, Puri, Pier Lorenzo, Palacios, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423270/
https://www.ncbi.nlm.nih.gov/pubmed/28067271
http://dx.doi.org/10.1038/ncomms13956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423270/
https://www.ncbi.nlm.nih.gov/pubmed/28067271
http://dx.doi.org/10.1038/ncomms13956

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