Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity

N-methyl D-aspartate receptors (NMDAR) play crucial role in normal brain function and pathogenesis of neurodegenerative and psychiatric disorders. Functional tetra-heteromeric NMDAR contains two obligatory GluN1 subunits and two identical or different non-GluN1 subunits that include six different ge...

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Detalles Bibliográficos
Autores principales: Bledsoe, Douglas, Tamer, Ceyhun, Mesic, Ivana, Madry, Christian, Klein, Bradley G., Laube, Bodo, Costa, Blaise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423295/
https://www.ncbi.nlm.nih.gov/pubmed/28536523
http://dx.doi.org/10.3389/fphar.2017.00229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423295/
https://www.ncbi.nlm.nih.gov/pubmed/28536523
http://dx.doi.org/10.3389/fphar.2017.00229

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