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NetLand: quantitative modeling and visualization of Waddington’s epigenetic landscape using probabilistic potential

SUMMARY: Waddington’s epigenetic landscape is a powerful metaphor for cellular dynamics driven by gene regulatory networks (GRNs). Its quantitative modeling and visualization, however, remains a challenge, especially when there are more than two genes in the network. A software tool for Waddington’s...

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Detalles Bibliográficos
Autores principales: Guo, Jing, Lin, Feng, Zhang, Xiaomeng, Tanavde, Vivek, Zheng, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423452/
https://www.ncbi.nlm.nih.gov/pubmed/28108450
http://dx.doi.org/10.1093/bioinformatics/btx022