Cargando…

Challenges and Prospects for Helper-Dependent Adenoviral Vector-Mediated Gene Therapy

Helper-dependent adenoviral (HDAd) vectors that are devoid of all viral coding sequences are promising non-integrating vectors for gene therapy because they efficiently transduce a variety of cell types in vivo, have a large cloning capacity, and drive long-term transgene expression without chronic...

Descripción completa

Detalles Bibliográficos
Autores principales: Piccolo, Pasquale, Brunetti-Pierri, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423471/
https://www.ncbi.nlm.nih.gov/pubmed/28548064
http://dx.doi.org/10.3390/biomedicines2020132