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Challenges and Prospects for Helper-Dependent Adenoviral Vector-Mediated Gene Therapy
Helper-dependent adenoviral (HDAd) vectors that are devoid of all viral coding sequences are promising non-integrating vectors for gene therapy because they efficiently transduce a variety of cell types in vivo, have a large cloning capacity, and drive long-term transgene expression without chronic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423471/ https://www.ncbi.nlm.nih.gov/pubmed/28548064 http://dx.doi.org/10.3390/biomedicines2020132 |