Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation

Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare variant of HCC that most frequently affects young adults. Because of its rarity and an absence of preclinical models, our understanding of FL-HCC is limited. Our objective was to analyze chromosomal alterations and dysregulated gene expressio...

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Detalles Bibliográficos
Autores principales: Sorenson, Eric C., Khanin, Raya, Bamboat, Zubin M., Cavnar, Michael J., Kim, Teresa S., Sadot, Eran, Zeng, Shan, Greer, Jonathan B., Seifert, Adrian M., Cohen, Noah A., Crawley, Megan H., Green, Benjamin L., Klimstra, David S., DeMatteo, Ronald P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423588/
https://www.ncbi.nlm.nih.gov/pubmed/28486549
http://dx.doi.org/10.1371/journal.pone.0176562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423588/
https://www.ncbi.nlm.nih.gov/pubmed/28486549
http://dx.doi.org/10.1371/journal.pone.0176562

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