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Model-based analysis of N-glycosylation in Chinese hamster ovary cells

The Chinese hamster ovary (CHO) cell is the gold standard for manufacturing of glycosylated recombinant proteins for production of biotherapeutics. The similarity of its glycosylation patterns to the human versions enable the products of this cell line favorable pharmacokinetic properties and lower...

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Detalles Bibliográficos
Autores principales: Krambeck, Frederick J., Bennun, Sandra V., Andersen, Mikael R., Betenbaugh, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423595/
https://www.ncbi.nlm.nih.gov/pubmed/28486471
http://dx.doi.org/10.1371/journal.pone.0175376