Acetyl group coordinated progression through the catalytic cycle of an arylalkylamine N-acetyltransferase

The transfer of an acetyl group from acetyl-CoA to an acceptor amine is a ubiquitous biochemical transformation catalyzed by Gcn5-related N-acetyltransferases (GNATs). Although it is established that the reaction proceeds through a sequential ordered mechanism, the role of the acetyl group in drivin...

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Detalles Bibliográficos
Autores principales: Aboalroub, Adam A., Bachman, Ashleigh B., Zhang, Ziming, Keramisanou, Dimitra, Merkler, David J., Gelis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423648/
https://www.ncbi.nlm.nih.gov/pubmed/28486510
http://dx.doi.org/10.1371/journal.pone.0177270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423648/
https://www.ncbi.nlm.nih.gov/pubmed/28486510
http://dx.doi.org/10.1371/journal.pone.0177270

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