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Acetyl group coordinated progression through the catalytic cycle of an arylalkylamine N-acetyltransferase
The transfer of an acetyl group from acetyl-CoA to an acceptor amine is a ubiquitous biochemical transformation catalyzed by Gcn5-related N-acetyltransferases (GNATs). Although it is established that the reaction proceeds through a sequential ordered mechanism, the role of the acetyl group in drivin...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423648/ https://www.ncbi.nlm.nih.gov/pubmed/28486510 http://dx.doi.org/10.1371/journal.pone.0177270 |