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HAT2 mediates histone H4K4 acetylation and affects micrococcal nuclease sensitivity of chromatin in Leishmania donovani

Histone post-translational modifications (PTMs) such as acetylation and methylation are known to affect chromatin higher order structures. Primary targets of these modifications include basic residues present at N-terminus tail region of core histones. Four histone acetyltransferase (HAT) genes have...

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Detalles Bibliográficos
Autores principales: Jha, Pravin K., Khan, Mohd. Imran, Mishra, Anshul, Das, Pradeep, Sinha, Kislay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423686/
https://www.ncbi.nlm.nih.gov/pubmed/28486547
http://dx.doi.org/10.1371/journal.pone.0177372