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Mapping of the Lassa virus LAMP1 binding site reveals unique determinants not shared by other old world arenaviruses

Cell entry of many enveloped viruses occurs by engagement with cellular receptors, followed by internalization into endocytic compartments and pH-induced membrane fusion. A previously unnoticed step of receptor switching was found to be critical during cell entry of two devastating human pathogens:...

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Detalles Bibliográficos
Autores principales: Israeli, Hadar, Cohen-Dvashi, Hadas, Shulman, Anastasiya, Shimon, Amir, Diskin, Ron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423696/
https://www.ncbi.nlm.nih.gov/pubmed/28448640
http://dx.doi.org/10.1371/journal.ppat.1006337