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Plasmodium actin is incompletely folded by heterologous protein-folding machinery and likely requires the native Plasmodium chaperonin complex to enter a mature functional state

Actin filament turnover underpins several processes in the life cycle of the malaria parasite, Plasmodium falciparum. Polymerization and depolymerization are especially important for gliding motility, a substrate-dependent form of cell movement that underpins the protozoan parasite’s ability to diss...

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Detalles Bibliográficos
Autores principales: Olshina, Maya A., Baumann, Hella, Willison, Keith R., Baum, Jake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423778/
https://www.ncbi.nlm.nih.gov/pubmed/26443825
http://dx.doi.org/10.1096/fj.15-276618