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The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer

The loss of E-cadherin causes dysfunction of the cell-cell junction machinery, which is an initial step in epithelial-to-mesenchymal transition (EMT), facilitating cancer cell invasion and the formation of metastases. A set of transcriptional repressors of E-cadherin (CDH1) gene expression, includin...

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Detalles Bibliográficos
Autores principales: He, Yi, Northey, Jason J., Pelletier, Ariane, Kos, Zuzana, Meunier, Liliane, Haibe-Kains, Benjamin, Mes-Masson, Anne-Marie, Côté, Jean-François, Siegel, Peter M., Lamarche-Vane, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423781/
https://www.ncbi.nlm.nih.gov/pubmed/28135249
http://dx.doi.org/10.1038/onc.2016.492