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A single-layer platform for Boolean logic and arithmetic through DNA excision in mammalian cells
Genetic circuits engineered for mammalian cells often require extensive fine-tuning to perform their intended functions. To overcome this problem, we present a generalizable biocomputing platform that can engineer genetic circuits which function in human cells with minimal optimization. We used our...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423837/ https://www.ncbi.nlm.nih.gov/pubmed/28346402 http://dx.doi.org/10.1038/nbt.3805 |