Predominance of Weakly Cytotoxic, T-bet(Low)Eomes(Neg) CD8(+) T-cells in Human Gastrointestinal Mucosa: Implications for HIV Infection

The gastrointestinal mucosa is an important site of HIV acquisition, viral replication and pathogenesis. Immune cells in mucosal tissues frequently differ in phenotype and function from their non-mucosal counterparts. Although perforin-mediated cytotoxicity as measured in blood is a recognized corre...

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Detalles Bibliográficos
Autores principales: Kiniry, Brenna E., Ganesh, Anupama, Critchfield, J. William, Hunt, Peter W., Hecht, Frederick M., Somsouk, Ma, Deeks, Steven G., Shacklett, Barbara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423867/
https://www.ncbi.nlm.nih.gov/pubmed/27827375
http://dx.doi.org/10.1038/mi.2016.100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423867/
https://www.ncbi.nlm.nih.gov/pubmed/27827375
http://dx.doi.org/10.1038/mi.2016.100

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