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The Role of APP in Structural Spine Plasticity

Amyloid precursor protein (APP) is a transmembrane protein highly expressed in neurons. The full-length protein has cell-adhesion and receptor-like properties, which play roles in synapse formation and stability. Furthermore, APP can be cleaved by several proteases into numerous fragments, many of w...

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Detalles Bibliográficos
Autores principales: Montagna, Elena, Dorostkar, Mario M., Herms, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423954/
https://www.ncbi.nlm.nih.gov/pubmed/28539872
http://dx.doi.org/10.3389/fnmol.2017.00136