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The Role of APP in Structural Spine Plasticity
Amyloid precursor protein (APP) is a transmembrane protein highly expressed in neurons. The full-length protein has cell-adhesion and receptor-like properties, which play roles in synapse formation and stability. Furthermore, APP can be cleaved by several proteases into numerous fragments, many of w...
Autores principales: | Montagna, Elena, Dorostkar, Mario M., Herms, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423954/ https://www.ncbi.nlm.nih.gov/pubmed/28539872 http://dx.doi.org/10.3389/fnmol.2017.00136 |
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