Direct visualization of Bcl-2 family protein interactions using live cell fluorescent protein redistribution assays

Bcl-2 family proteins have important roles in tumor initiation, progression and resistance to therapy. Pro-survival Bcl-2 proteins are regulated by their interactions with pro-death BH3-only proteins making these protein–protein interactions attractive therapeutic targets. Although these interaction...

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Detalles Bibliográficos
Autores principales: Wong, C, Anderson, D J, Lee, E F, Fairlie, W D, Ludlam, M J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424096/
https://www.ncbi.nlm.nih.gov/pubmed/22460384
http://dx.doi.org/10.1038/cddis.2012.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424096/
https://www.ncbi.nlm.nih.gov/pubmed/22460384
http://dx.doi.org/10.1038/cddis.2012.28

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