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Met degradation by SAIT301, a Met monoclonal antibody, reduces the invasion and migration of nasopharyngeal cancer cells via inhibition of EGR-1 expression

Nasopharyngeal carcinoma (NPC) is a common malignant tumor with high invasive and metastatic potential. The hepatocyte growth factor (HGF)-Met signaling pathway has a critical role in mediating the invasive growth of many different types of cancer, including head and neck squamous cell carcinoma. HG...

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Detalles Bibliográficos
Autores principales: Lee, B-S, Kang, S, Kim, K-A, Song, Y-J, Cheong, K H, Cha, H-Y, Kim, C-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424102/
https://www.ncbi.nlm.nih.gov/pubmed/24722284
http://dx.doi.org/10.1038/cddis.2014.119