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Resistance to the tyrosine kinase inhibitor axitinib is associated with increased glucose metabolism in pancreatic adenocarcinoma

Alterations in energy (glucose) metabolism are key events in the development and progression of cancer. In pancreatic adenocarcinoma (PDAC) cells, we investigated changes in glucose metabolism induced by resistance to the receptor tyrosine kinase inhibitor (RTKI) axitinib. Here, we show that human c...

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Detalles Bibliográficos
Autores principales: Hudson, C D, Hagemann, T, Mather, S J, Avril, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424106/
https://www.ncbi.nlm.nih.gov/pubmed/24722285
http://dx.doi.org/10.1038/cddis.2014.125