Selective inhibition of protein kinase C β(2) attenuates the adaptor P66(Shc)-mediated intestinal ischemia–reperfusion injury

Apoptosis is a major mode of cell death occurring during ischemia–reperfusion (I/R) induced injury. The p66(Shc) adaptor protein, which is mediated by PKCβ, has an essential role in apoptosis under oxidative stress. This study aimed to investigate the role of PKCβ(2)/p66(Shc) pathway in intestinal I...

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Detalles Bibliográficos
Autores principales: Chen, Z, Wang, G, Zhai, X, Hu, Y, Gao, D, Ma, L, Yao, J, Tian, X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424109/
https://www.ncbi.nlm.nih.gov/pubmed/24722289
http://dx.doi.org/10.1038/cddis.2014.131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424109/
https://www.ncbi.nlm.nih.gov/pubmed/24722289
http://dx.doi.org/10.1038/cddis.2014.131

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