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Selective inhibition of protein kinase C β(2) attenuates the adaptor P66(Shc)-mediated intestinal ischemia–reperfusion injury
Apoptosis is a major mode of cell death occurring during ischemia–reperfusion (I/R) induced injury. The p66(Shc) adaptor protein, which is mediated by PKCβ, has an essential role in apoptosis under oxidative stress. This study aimed to investigate the role of PKCβ(2)/p66(Shc) pathway in intestinal I...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424109/ https://www.ncbi.nlm.nih.gov/pubmed/24722289 http://dx.doi.org/10.1038/cddis.2014.131 |